Chlorella vulgaris single-celled green algae; It has been used for many years in various fields, including the pharmaceutical and cosmetics industries. This microalgae is supplied as a dietary supplement, additive and food emulsion in the form of capsules, tablets, powders and extracts and is used for medical treatments.
Vitamin C or ascorbic acid and its derivatives also play an important role in making collagen, strengthening skin texture and beauty. This vitamin is a natural antioxidant that protects the skin from sunlight and can stimulate collagen production.
Given the importance of the skin as the body’s first line of defense and the positive effects of marine microalgae such as Chlorella vulgaris, the researchers conducted a study on the effects of algae extract on the expression of collagen I and III genes in skin fibroblast cells.
This study was performed at the National Center for Genetic and Biological Resources of Iran and after extracting the algae, its extract with different concentrations was added to the culture medium of a type of skin cell. The researchers repeated the experiment by adding vitamin C and compared the effects of the two substances on collagen gene expression.
The results of this study showed that algae extract in different concentrations is not toxic to skin cells and has no cytotoxic effect.
The study also found that algae extract increased collagen gene expression. Comparing its effect with the effect of vitamin C showed that algae extract has a greater effect on the expression of collagen I and III genes than vitamin C and can double the expression of this gene.
According to the researchers; Chlorella vulgaris extract can be used as a natural alternative to chemical anti-aging products due to its non-toxic effect on cells, and these results can be useful for the production of various cosmetic products.
In this study, Soodabeh Abdolbaqian and Ali Machinchian Moradi, from the Faculty of Natural Resources and Environment, Islamic Azad University, Research Sciences Branch, Shahla Jamili; Researcher of Iran Fisheries Science Research Institute and Azadeh Manaei; Researchers from the Medicinal Plants Research Center of Tehran University of Medical Sciences participated.
The findings of this study were published in a scientific research article entitled “Expression changes of collagen I and III genes in human skin fibroblasts due to extracts of chlorella vulgaris and its comparison with vitamin C” in the Journal of Marine Biology, Islamic Azad University, Ahvaz Branch. .