Transfer of father-to-child traits without divine interference

According to reports EconomyOnline According to ISNA, this issue is related to epigenetics. Some molecules attach to the worlds and act like a power button, controlling parts of the world to be used, but we did not know which of these molecules had the characteristics created during the father’s life and experiences. They carry themselves and are transmitted to the embryo by sperm.

“The highlight of this study is the discovery of a non-diurnal agent that allows sperm to maintain their father’s environmental conditions, such as diet, and to embryo,” said Sarah Kimmins, an epigenetic specialist at McGill University. Transfers.

Using epigenetics, Ariane Lismer, a fellow ophthalmologist, and mice showed that a diet with folic acid deficiency can alter histone molecules in sperm and transmit their effects to the embryo. Histones are simply proteins around which the brain is wrapped.

In mammals, when sperm are produced, most histones are released to make a smaller cell, but a small percentage of these histones remain (1% in mice and 15% in humans). These residual proteins provide scaffolding for the teeth in parts of the sperm that are involved in sperm production and function, metabolism, and embryo formation, and help cellular mechanisms use the instructions in the teeth.

The chemical modification of these histones, the most common of which is “methylation”, allows or prevents the reading of the diagonal. Religious reading leads to the production of protein products. Improper diet can alter the methylation status of these histones.

This is why folic acid is recommended during pregnancy because maternal folic acid helps stabilize methylation in the baby’s teeth.

By giving folic acid-containing diets to male mice after weaning, the scientists were able to study the changes in their sperm histones as well as the resulting embryos. Histone changes were also present in emerging embryos.

“Until now, no one has been able to understand how environmental conditions are transmitted to the embryo through sperm,” says Lizmer.

The team also found that these effects could increase birth defects.

Interestingly, there are also congenital defects observed in mice, such as inadequate growth at birth and spinal deformities in human populations with folic acid deficiency.

Scientists hope to find new ways to prevent these problems and diseases by increasing their knowledge of hereditary mechanisms, but much research needs to be done by then.

The research is published in the journal Developmental Cell.

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